Give your dog a special treat each time you leave, like a puzzle toy stuffed with peanut butter. Only give them this treat when you're gone, and take it away when you get home. Make your comings and goings low-key without a lot of greeting. Ignore your pup for the first few minutes after you get home. Leave some recently worn clothes out that smell like you. Consider giving your pet over-the-counter natural calming supplements. They may start to get nervous when they see signs you're about to leave, like putting on your shoes or picking up your keys. So do those things, but then don't leave. Put on your shoes and then sit down at the table. Pick up your keys and watch TV. Do this over and over many times a day. When your dog starts to feel less anxious about that, you can slowly start to disappear. Always act calm when you leave and when you return. Make sure your pet gets lots of exercise every day. A tired, happy dog will be less stressed when you leave. It's also key that you challenge your pet's mind. Play training games and fetch. Use interactive puzzles. Work their mind as well as their body. That will keep them busy, happy, and too tired to be anxious while you're gone.