What is the miracle arthritis drug for dogs?
Dedric Kozey
2025-08-05 19:34:44
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Librela is the first monoclonal antibody the FDA has approved for use in dogs. The FDA approved Librela for the control of pain associated with osteoarthritis in dogs. Librela can help control the pain associated with the condition. Bedinvetmab, the active ingredient in Librela, works by binding to and inhibiting the biological activity of a protein called canine nerve growth factor, which has been found to be elevated in dogs with OA and is involved in the regulation of pain. When bedinvetmab binds to NGF, it prevents the pain signal from reaching the brain. The weight of evidence from the two field studies demonstrated that Librela is effective at controlling pain associated with OA in dogs when at least two doses are given 28 days apart. OA is the most common form of arthritis in dogs, it is estimated that it affects at least 25 percent of dogs at some point in their lifetime. Librela is given by subcutaneous injection once a month and dosed by weight range to target a minimum dose of 0.5 mg/kg.