Mice can sense extremely fast and subtle changes in the structure of odours and use this to guide their behaviour. Odour plumes, like the steam off a hot cup of coffee, are complex and often turbulent structures, and can convey meaningful information about an animal’s surroundings, like the movements of a predator or the location of food sources. But it has previously been assumed that mammalian brains can’t fully process these temporal changes in smell because they happen so rapidly, much faster than an animal can sniff. Using behavioural experiments where mice were exposed to incredibly short bursts of odour, neural imaging, electrophysiology and computer models, the scientists found that mice can, in fact, detect very rapid fluctuations within odour plumes, at rates previously not thought possible. They also showed that mice can use this information to distinguish whether odours are coming from the same or different sources, even if they are very close to each other. Andreas Schaefer says: It isn’t just processing chemicals from odours but can also calculate information about physical distance and source. This suggests that the mammalian olfactory system, responsible for the sense of smell, is also key in processing the awareness of physical space and surroundings, guiding decisions important to survival.