How to stop hormonal aggression in dogs?

It does not necessarily mean that modulating these hormones will resolve a dog’s aggressive behavior. Discussions with some of my colleagues who have used oxytocin to treat fear-related or aggressive behavior revealed that some cases were met with success, but in other cases, oxytocin did not appear to be helpful. Currently, I still rely on my serotonin-modulating medications in addition to behavior modification exercises to treat a dog who exhibits aggressive behavior. More studies are needed to test the efficacy of oxytocin in treatment of aggressive behavior and if blocking or reducing vasopressin levels can be another treatment option. Behavior involves a complex interaction of genetics, learned experiences, and physiological responses. The authors of this study discussed other studies in which administration of vasopressin at times inhibited aggressive behavior. Remember that aggressive behavior is distance-increasing behavior and can be a part of a normal behavior repertoire in response to what the dog has perceived as a threat. The study found that high levels of vasopressin were associated with the higher degree of aggression exhibited during the trials. The service dogs had higher blood oxytocin levels than normal pet dogs, which may imply that the service dogs are calmer due to higher levels of oxytocin in their system.