Often, the spay and neuter take place at a very young age for pets, at four to six months. However, studies have shown that this may not be the best age to spay or neuter your dog. The wide margin of maturation of dogs varies considerably, as toy breed dogs mature sexually as early as six to nine months of age whereas large and giant breeds may mature as late as 16-18 months of age. An age of six to nine months of age may be appropriate for neutering or spaying a toy breed puppy or small breed puppy but a larger or giant breed may need to wait until they are near or over 12-18 months of age. Different breeds and different sized dogs mature at different ages, which means that early spay/neuter may not be bad for all dogs. The end conclusion is that generally, the larger breeds had possibly more to risk in future health conditions in than small or toy breeds of dogs due to early spaying or neutering since they mature at a later age. When considering whether to spay or neuter your dog, with today’s information about the possible effects of age at the time of surgery on their future health, it is ideal to have a detailed discussion with your veterinarian to determine what is best for your dog.