Your vet will conduct a thorough assessment to determine the cause of your pet’s itching, but anti-itch medications, such as Oclacitinib (Apoquel), and Prednisolone may be prescribed to reduce the itching. Antihistamines can also be used in some cases, as well as medicated shampoos and topical ointments. Colloidal oatmeal has been shown to have natural anti-inflammatory properties that can help to ease redness, swelling, and itchiness. Aloe Vera 100% aloe vera (that doesn’t contain alcohol) is a great natural remedy for relieving redness and drawing heat away from the skin, which is great for pets that have been itching a lot. To reduce itching, there are a few medications that may help; Lokivetmab (Cytopoint). This is a monoclonal antibody therapy, designed to block the major itch chemical in the skin and is highly specific against skin itching with very few side effects. Oclacitinib (Apoquel). This aims to stop the activation of itch-causing inflammatory chemicals. Prednisolone. This is a steroid with potent anti-inflammatory properties, often used for more severe conditions. Antihistamines. These may also be prescribed for some pets, but may not be suitable in all cases, their effect is highly variable in animals.