What are the downsides of NexGard?
Charlene Dooley
2025-09-21 16:58:30
Count answers
: 19
Isoxazoline products have been associated with neurologic adverse reactions, including muscle tremors, ataxia, and seizures in some dogs and cats.
Although most dogs and cats haven’t had neurologic adverse reactions, seizures may occur in animals without a prior history.
Nexgard (afoxolaner) tablets for dogs
Nexgard Plus (afoxolaner, moxidectin, and pyrantel) chewable tablets for dogs
If your dog or cat experiences any adverse event while using an isoxazoline product, first consult your veterinarian.
The FDA continues to monitor adverse drug event reports for these products and encourages pet owners and veterinarians to report adverse drug events.
You can do this by reporting to the drugs’ manufacturers, who are required to report this information to the FDA, or by submitting a report directly to the FDA.
To report suspected adverse drug events for these products and/or obtain a copy of the Safety Data Sheet (SDS) or for technical assistance, contact the appropriate manufacturers at the following phone numbers:
Boehringer Ingelheim (Nexgard): 888-637-4251
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