As dogs age, some show a significant increase in anxiety and other behavioral issues. With a potential decrease in their senses of hearing, sight and smell, dogs can startle more easily. It may be more generalized, with your dog seeming to enjoy things less or even being jumpier. If your dog is showing more extensive signs of anxiety—from panting, shaking, trembling and irritability to having sleep and appetite issues—you need to pay closer attention. It is recognized that increased anxiety is a distinct component of dogs that start to experience a form of dementia called cognitive dysfunction syndrome (CDS) or canine cognitive dysfunction (CCD), similar to Alzheimer’s in humans. Other aspects of CDS can be summarized with the acronym DISHAA: Disorientation; Social Interactions; Sleep/wake cycles; House-soiling (learning and memory); Activity (change in levels); and Anxiety. Move slowly around your dogs and carefully approach them as sensory deficits (e.g., loss of hearing, sight) coupled with anxiety can make them irritable and even aggressive. They may feel abandoned at nighttime when you sleep or experience separation anxiety when you leave the house.