Is green lipped mussel better than glucosamine?

GLME is a natural product with multiple compounds. It has chondro-protective, gastro-protective and anti-inflammatory actions. It is effective in both osteoarthritis and rheumatoid arthritis. It has long-chain fatty acids and a wide range of therapeutic polysaccharides. It is a ‘basic food status’ product and thus, it is safe to consume even at higher doses and does not cause any serious adverse effects. On the other side, glucosamine is a single compound product. It has only mild anti-inflammatory activity and provides joint and cartilage protection. It is beneficial in Osteoarthritis only. Glucosamine intake can cause certain side effects such as: Upset stomach Nausea Diarrhea Constipation Skin reactions Headache Heartburn Drowsiness. Risks linked with the intake of glucosamine: People who are allergic to shellfish can have allergies with the intake of glucosamine.

The green-lipped mussel is not the best alternative because it contains very little of the active substances required. Green-lipped mussel also contains omega-3 fatty acids, glucosamine and chondroitin, but it contains very little of them. The daily dose of green-lipped mussel for a dog that weighs 20 kilograms contains only 0.15 mg of Omega-3 ETA. In comparison: The corresponding content in Nutrolin HIP & JOINT is 30 mg ETA, that is, 200 times more. The daily dose of freeze-dried green-lipped mussel for a dog that weighs 20 kilograms contains max. 4 mg chondroitin sulphate. In comparison: The daily dose of Nutrolin HIP & JOINT for a dog that weighs 20 kilograms includes 2 tablets of joint nutrient in addition to fish oil, the tablets contain a total of 440 mg chondroitin sulphate, that is, more than 100 times more than a corresponding dose of green-lipped mussel. It stated that omega-3 fatty acids from fish oil, glucosamine and chondroitin as well as green-lipped mussel have an anti-inflammatory effect and that they are therefore suitable for use in the treatment of pain resulting from arthrosis.

Glucosamine and Chondroitin are both naturally found in Green-lipped mussels. Glucosamine and chondroitin are both natural compounds that are found in healthy cartilage, which is the connective tissue that cushions joints. Glucosamine found in green-lipped mussels is similar to that in other sources, but its natural combination with other beneficial lipids and minerals in the mussels seems to enhance its effectiveness. The chondroitin in green-lipped mussels complements the action of the glucosamine. Regular intake of glucosamine from natural sources like green-lipped mussels, is thought to contribute to the maintenance of healthy joint function. The unique aspect of green-lipped mussel supplements is the natural combination of glucosamine and chondroitin with other beneficial nutrients, including omega-3 fatty acids and minerals. This holistic composition is believed to contribute to the overall effectiveness of the supplements in promoting joint health. Green-lipped mussels are a rich and unique source of glucosamine and chondroitin. Unlike other sources, green-lipped mussels provide these nutrients in a natural form, which many believe enhances their bioavailability and effectiveness. The glucosamine and chondroitin found in green-lipped mussels, combined with other beneficial nutrients in the mussels, represents a comprehensive natural approach to supporting joint health.

Both GLM and GS reduced OA symptoms and non-significantly altered the gut microbiota profile from baseline. We further confirm significant improvement in all OA outcome measures from T (0) to T (12) weeks for both the GLM and GS groups. The GSRS scores indicated that GIT function significantly improved over the 12 weeks duration with GLM and GS supplementation. This study suggests that nutritional supplements such as GLM and GS may regulate some of the metabolic and immunological activities of the GIT microbiota. The decrease in Clostridia, a potent modulator of colonic Th17 and CD4+ regulatory T cells, was consistent with a decrease in inflammation; improved GSRS scores and OA symptoms for these OA participants.