Anti-inflammatory medications, known as nonsteroidal anti-inflammatory drugs (NSAIDs), are frequently used to manage your dog’s condition and can offer a dramatic improvement in mobility and quality of life. There are many licenced drugs available that come in different formulations and are given in different ways and generally they are very well tolerated. However, as with all medications, side-effects can happen, but following advised dosing, as well as keeping a close eye on your dog’s appetite, toileting and thirst will significantly reduce the likelihood of them occurring. Developments in NSAIDs in the last decade have created more COX-2 selective drugs which should reduce the side effects seen, however adverse reactions can still happen. Combining a number of treatments is recognised as the most effective way of controlling pain with minimum side-effects. Owners are often hesitant to use NSAIDs due to publicity regarding potential side-effects, and will seek alternative options for pain control. We strongly suggest using a means of measuring pain before the treatment and after to ensure the goals of using it are met.