Some natural health practitioners say that parasite infections can be treated with a cleanse comprised of herbs and supplements. Very limited research exists on whether any natural ingredients may help treat parasite infections, but some people suggest the following herbal supplements may be beneficial: anise, thyme, rosemary, cumin, marjoram, barberry, berberine, black walnut, clove oil, mint, goldenseal, grapefruit seed extract, propolis, Oregon grape, wormwood. Some animal studies suggest that the following natural ingredients may have anti-parasitic effects: thyme, rosemary, cumin, marjoram, garlic, ginger, tongkat ali, wormwood, berberine, which is found in barberry, propolis, which is made by bees. According to a 2024 review, some animal studies found that probiotic therapy may play a possible role in treating parasitic infections by increasing the healthy bacteria in your gut and promoting antibacterial activity. Similarly, a 2017 review found that vitamin A, zinc, and selenium may reduce the severity of parasitic infections. Supplementing with these minerals and vitamins might, therefore, form part of a parasite cleanse. Eating garlic, ginger, and foods high in vitamin A, taking supplements, such as probiotics, vitamin A, zinc, and selenium, may also help treat parasites.